AniPhone screen may stop responding to touch because of a software glitch, a frozen app, a dirty or wet screen, a faulty screen protector, or physical damage to the display. Start by cleaning and drying the screen and removing any accessories that may interfere with touch sensitivity. If the problem continues, try restarting or force-restarting the iPhone. For persistent issues, especially after a drop or screen damage, the device may need professional inspection or screen repair.